BDBM50198370 CHEMBL223873::N-(2,6-dimethyl-phenyl)-5-phenylimidazo[1,5-a]pyrazine-8-amine::N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine::N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazine-8-amine

SMILES: Cc1cccc(C)c1Nc1ncc(-c2ccccc2)n2cncc12

InChI Key: InChIKey=KKYYLKPGILUPOA-UHFFFAOYSA-N

Data: 2 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198370 (CHEMBL223873 | N-(2,6-dimethyl-phenyl)-5-phenylimi...) Show SMILES Cc1cccc(C)c1Nc1ncc(-c2ccccc2)n2cncc12 Show InChI InChI=1S/C20H18N4/c1-14-7-6-8-15(2)19(14)23-20-18-11-21-13-24(18)17(12-22-20)16-9-4-3-5-10-16/h3-13H,1-2H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of cSrc by coupled spectrophotometric enzyme assay				Bioorg Med Chem 15: 868-85 (2006) Article DOI: 10.1016/j.bmc.2006.10.041 BindingDB Entry DOI: 10.7270/Q2DZ094H
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50198370 (CHEMBL223873 | N-(2,6-dimethyl-phenyl)-5-phenylimi...) Show SMILES Cc1cccc(C)c1Nc1ncc(-c2ccccc2)n2cncc12 Show InChI InChI=1S/C20H18N4/c1-14-7-6-8-15(2)19(14)23-20-18-11-21-13-24(18)17(12-22-20)16-9-4-3-5-10-16/h3-13H,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Inhibition of LCK (unknown origin)				Bioorg Med Chem 16: 10311-8 (2008) Article DOI: 10.1016/j.bmc.2008.10.041 BindingDB Entry DOI: 10.7270/Q2W37W5C
					More data for this Ligand-Target Pair				3D Structure (crystal)