BDBM50198389 1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(5-(4-(trifluoromethyl)phenyl)thiophen-2-yl)urea::CHEMBL244398

SMILES: CC1(C)[C@@H]2C[C@H]1C(CN1CCC(CC1)NC(=O)Nc1ccc(s1)-c1ccc(cc1)C(F)(F)F)=CC2

InChI Key: InChIKey=ZGEWBDMYBJHVOV-UNMCSNQZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198389   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human))	BDBM50198389 (1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...) Show SMILES CC1(C)[C@@H]2C[C@H]1C(CN1CCC(CC1)NC(=O)Nc1ccc(s1)-c1ccc(cc1)C(F)(F)F)=CC2 |c:36| Show InChI InChI=1S/C27H32F3N3OS/c1-26(2)20-8-5-18(22(26)15-20)16-33-13-11-21(12-14-33)31-25(34)32-24-10-9-23(35-24)17-3-6-19(7-4-17)27(28,29)30/h3-7,9-10,20-22H,8,11-16H2,1-2H3,(H2,31,32,34)/t20-,22-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 17: 697-701 (2007) Article DOI: 10.1016/j.bmcl.2006.10.088 BindingDB Entry DOI: 10.7270/Q2833RPB
					More data for this Ligand-Target Pair