BDBM50198390 1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(3-(trifluoromethoxy)phenyl)urea::CHEMBL244186

SMILES: CC1(C)[C@@H]2C[C@H]1C(CN1CCC(CC1)NC(=O)Nc1cccc(OC(F)(F)F)c1)=CC2

InChI Key: InChIKey=KSTPUYRHIGGZRH-JXFKEZNVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198390   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human))	BDBM50198390 (1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en...) Show SMILES CC1(C)[C@@H]2C[C@H]1C(CN1CCC(CC1)NC(=O)Nc1cccc(OC(F)(F)F)c1)=CC2 |c:31| Show InChI InChI=1S/C23H30F3N3O2/c1-22(2)16-7-6-15(20(22)12-16)14-29-10-8-17(9-11-29)27-21(30)28-18-4-3-5-19(13-18)31-23(24,25)26/h3-6,13,16-17,20H,7-12,14H2,1-2H3,(H2,27,28,30)/t16-,20-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 17: 697-701 (2007) Article DOI: 10.1016/j.bmcl.2006.10.088 BindingDB Entry DOI: 10.7270/Q2833RPB
					More data for this Ligand-Target Pair