BDBM50198416 1-(naphthalen-2-yl)-3-(1-phenethylpiperidin-4-yl)urea::CHEMBL387596
SMILES: O=C(NC1CCN(CCc2ccccc2)CC1)Nc1ccc2ccccc2c1
InChI Key: InChIKey=KEKNEWNFYWUQAH-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human)) | BDBM50198416 (1-(naphthalen-2-yl)-3-(1-phenethylpiperidin-4-yl)u...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Curated by ChEMBL | Assay Description Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTPgammaS binding assay | Bioorg Med Chem Lett 17: 697-701 (2007) Article DOI: 10.1016/j.bmcl.2006.10.088 BindingDB Entry DOI: 10.7270/Q2833RPB | |||||||||||
More data for this Ligand-Target Pair |