BDBM50198502 (S)-6-(4-chlorophenyl)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methylnicotinamide::CHEMBL217820

SMILES: CN(C)Cc1ccc2C[C@H](CCc2c1)N(C)C(=O)c1ccc(nc1)-c1ccc(Cl)cc1

InChI Key: InChIKey=NYUKWJXYAADYOO-DEOSSOPVSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50198502 ((S)-6-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...) Show SMILES CN(C)Cc1ccc2C[C@H](CCc2c1)N(C)C(=O)c1ccc(nc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H28ClN3O/c1-29(2)17-18-4-5-21-15-24(12-8-20(21)14-18)30(3)26(31)22-9-13-25(28-16-22)19-6-10-23(27)11-7-19/h4-7,9-11,13-14,16,24H,8,12,15,17H2,1-3H3/t24-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Functional antagonism of MCH-R1 expressed in HEK293 cells				Bioorg Med Chem Lett 17: 814-8 (2007) Article DOI: 10.1016/j.bmcl.2006.10.053 BindingDB Entry DOI: 10.7270/Q2R2111C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50198502 ((S)-6-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...) Show SMILES CN(C)Cc1ccc2C[C@H](CCc2c1)N(C)C(=O)c1ccc(nc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H28ClN3O/c1-29(2)17-18-4-5-21-15-24(12-8-20(21)14-18)30(3)26(31)22-9-13-25(28-16-22)19-6-10-23(27)11-7-19/h4-7,9-11,13-14,16,24H,8,12,15,17H2,1-3H3/t24-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of binding to serotonin receptor 5HT2C				Bioorg Med Chem Lett 17: 814-8 (2007) Article DOI: 10.1016/j.bmcl.2006.10.053 BindingDB Entry DOI: 10.7270/Q2R2111C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50198502 ((S)-6-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...) Show SMILES CN(C)Cc1ccc2C[C@H](CCc2c1)N(C)C(=O)c1ccc(nc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H28ClN3O/c1-29(2)17-18-4-5-21-15-24(12-8-20(21)14-18)30(3)26(31)22-9-13-25(28-16-22)19-6-10-23(27)11-7-19/h4-7,9-11,13-14,16,24H,8,12,15,17H2,1-3H3/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of binding to hERG				Bioorg Med Chem Lett 17: 814-8 (2007) Article DOI: 10.1016/j.bmcl.2006.10.053 BindingDB Entry DOI: 10.7270/Q2R2111C
					More data for this Ligand-Target Pair