BDBM50198614 CHEMBL3901022

SMILES: COc1cc(OCc2ccccc2)ccc1\C=C\C(=O)CC(=O)\C=C\c1ccc2cc[nH]c2c1

InChI Key: InChIKey=ZAPPNMGPHQBOBC-SDCOAONHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau (Homo sapiens (Human))	BDBM50198614 (CHEMBL3901022) Show SMILES COc1cc(OCc2ccccc2)ccc1\C=C\C(=O)CC(=O)\C=C\c1ccc2cc[nH]c2c1 Show InChI InChI=1S/C29H25NO4/c1-33-29-19-27(34-20-22-5-3-2-4-6-22)14-11-24(29)10-13-26(32)18-25(31)12-8-21-7-9-23-15-16-30-28(23)17-21/h2-17,19,30H,18,20H2,1H3/b12-8+,13-10+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Doshisha University Curated by ChEMBL					Assay Description Inhibition of recombinant human TAU three-repeat microtubule-binding domain aggregation expressed in Escherichia coli after 16 hrs by thioflavin T fl...				Bioorg Med Chem Lett 26: 5024-5028 (2016) Article DOI: 10.1016/j.bmcl.2016.08.092 BindingDB Entry DOI: 10.7270/Q2833V0M
					More data for this Ligand-Target Pair