BDBM50198619 CHEMBL3970179
SMILES: COc1cc(O)cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)c1
InChI Key: InChIKey=DCPJRIGGZGIXET-XOKGJFMYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tau (Homo sapiens (Human)) | BDBM50198619 (CHEMBL3970179) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Doshisha University Curated by ChEMBL | Assay Description Inhibition of recombinant human TAU three-repeat microtubule-binding domain aggregation expressed in Escherichia coli after 16 hrs by thioflavin T fl... | Bioorg Med Chem Lett 26: 5024-5028 (2016) Article DOI: 10.1016/j.bmcl.2016.08.092 BindingDB Entry DOI: 10.7270/Q2833V0M | |||||||||||
More data for this Ligand-Target Pair |