BDBM50198626 CHEMBL3950384

SMILES: COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc3cc[nH]c3c2)ccc1O

InChI Key: InChIKey=SIABTKWBOMYBGS-FCXRPNKRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau (Homo sapiens (Human))	BDBM50198626 (CHEMBL3950384) Show SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc3cc[nH]c3c2)ccc1O Show InChI InChI=1S/C22H19NO4/c1-27-22-13-16(5-9-21(22)26)4-8-19(25)14-18(24)7-3-15-2-6-17-10-11-23-20(17)12-15/h2-13,23,26H,14H2,1H3/b7-3+,8-4+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Doshisha University Curated by ChEMBL					Assay Description Inhibition of recombinant human TAU three-repeat microtubule-binding domain aggregation expressed in Escherichia coli after 16 hrs by thioflavin T fl...				Bioorg Med Chem Lett 26: 5024-5028 (2016) Article DOI: 10.1016/j.bmcl.2016.08.092 BindingDB Entry DOI: 10.7270/Q2833V0M
					More data for this Ligand-Target Pair