BDBM50198631 CHEMBL3938007

SMILES: COc1cc(OCC2CCCO2)ccc1\C=C\C(=O)CC(=O)\C=C\c1ccc2cc[nH]c2c1

InChI Key: InChIKey=RTQXVDGQEZRUPW-FWMCCXIMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau (Homo sapiens (Human))	BDBM50198631 (CHEMBL3938007) Show SMILES COc1cc(OCC2CCCO2)ccc1\C=C\C(=O)CC(=O)\C=C\c1ccc2cc[nH]c2c1 Show InChI InChI=1S/C27H27NO5/c1-31-27-17-24(33-18-25-3-2-14-32-25)11-8-21(27)7-10-23(30)16-22(29)9-5-19-4-6-20-12-13-28-26(20)15-19/h4-13,15,17,25,28H,2-3,14,16,18H2,1H3/b9-5+,10-7+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Doshisha University Curated by ChEMBL					Assay Description Inhibition of recombinant human TAU three-repeat microtubule-binding domain aggregation expressed in Escherichia coli after 16 hrs by thioflavin T fl...				Bioorg Med Chem Lett 26: 5024-5028 (2016) Article DOI: 10.1016/j.bmcl.2016.08.092 BindingDB Entry DOI: 10.7270/Q2833V0M
					More data for this Ligand-Target Pair