BDBM50198688 CHEMBL3929137

SMILES: Fc1ccc(\C=C2/CCCCc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)NC2CCN(CC2)c2ccccn2)cc1

InChI Key: InChIKey=GYTHQNSLEWSFBB-ZBJSNUHESA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198688   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198688 (CHEMBL3929137) Show SMILES Fc1ccc(\C=C2/CCCCc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)NC2CCN(CC2)c2ccccn2)cc1 Show InChI InChI=1S/C32H30Cl2FN5O/c33-23-10-13-28(27(34)20-23)40-31-22(19-21-8-11-24(35)12-9-21)5-1-2-6-26(31)30(38-40)32(41)37-25-14-17-39(18-15-25)29-7-3-4-16-36-29/h3-4,7-13,16,19-20,25H,1-2,5-6,14-15,17-18H2,(H,37,41)/b22-19+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human cannabinoid receptor 1 expressed in HEK293 cells assessed as increase in forskolin-induced cAMP production preincub...				Bioorg Med Chem Lett 26: 5346-5349 (2016) Article DOI: 10.1016/j.bmcl.2016.09.025 BindingDB Entry DOI: 10.7270/Q2MC9207
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198688 (CHEMBL3929137) Show SMILES Fc1ccc(\C=C2/CCCCc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)NC2CCN(CC2)c2ccccn2)cc1 Show InChI InChI=1S/C32H30Cl2FN5O/c33-23-10-13-28(27(34)20-23)40-31-22(19-21-8-11-24(35)12-9-21)5-1-2-6-26(31)30(38-40)32(41)37-25-14-17-39(18-15-25)29-7-3-4-16-36-29/h3-4,7-13,16,19-20,25H,1-2,5-6,14-15,17-18H2,(H,37,41)/b22-19+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human cannabinoid receptor 2 expressed in HEK293 cells assessed as increase in forskolin-induced cAMP production preincub...				Bioorg Med Chem Lett 26: 5346-5349 (2016) Article DOI: 10.1016/j.bmcl.2016.09.025 BindingDB Entry DOI: 10.7270/Q2MC9207
					More data for this Ligand-Target Pair