BDBM50198691 CHEMBL3923909

SMILES: Fc1ccc(\C=C2/CCCCc3c(nn(c23)-c2ccc(Cl)c(Cl)c2)C(=O)NC2(CC2)c2ccccn2)cc1

InChI Key: InChIKey=KLLWBIAQONUJSO-LVZFUZTISA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198691 (CHEMBL3923909) Show SMILES Fc1ccc(\C=C2/CCCCc3c(nn(c23)-c2ccc(Cl)c(Cl)c2)C(=O)NC2(CC2)c2ccccn2)cc1 Show InChI InChI=1S/C30H25Cl2FN4O/c31-24-13-12-22(18-25(24)32)37-28-20(17-19-8-10-21(33)11-9-19)5-1-2-6-23(28)27(36-37)29(38)35-30(14-15-30)26-7-3-4-16-34-26/h3-4,7-13,16-18H,1-2,5-6,14-15H2,(H,35,38)/b20-17+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human cannabinoid receptor 1 expressed in HEK293 cells assessed as increase in forskolin-induced cAMP production preincub...				Bioorg Med Chem Lett 26: 5346-5349 (2016) Article DOI: 10.1016/j.bmcl.2016.09.025 BindingDB Entry DOI: 10.7270/Q2MC9207
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198691 (CHEMBL3923909) Show SMILES Fc1ccc(\C=C2/CCCCc3c(nn(c23)-c2ccc(Cl)c(Cl)c2)C(=O)NC2(CC2)c2ccccn2)cc1 Show InChI InChI=1S/C30H25Cl2FN4O/c31-24-13-12-22(18-25(24)32)37-28-20(17-19-8-10-21(33)11-9-19)5-1-2-6-23(28)27(36-37)29(38)35-30(14-15-30)26-7-3-4-16-34-26/h3-4,7-13,16-18H,1-2,5-6,14-15H2,(H,35,38)/b20-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	807	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human cannabinoid receptor 2 expressed in HEK293 cells assessed as increase in forskolin-induced cAMP production preincub...				Bioorg Med Chem Lett 26: 5346-5349 (2016) Article DOI: 10.1016/j.bmcl.2016.09.025 BindingDB Entry DOI: 10.7270/Q2MC9207
					More data for this Ligand-Target Pair