BDBM50198727 CHEMBL3905508

SMILES: C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)CC(N)=O)-c1ccc(Cl)cc1Cl)c1ccccn1

InChI Key: InChIKey=UVZIHKAXDURETI-MIQLPHMESA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198727   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198727 (CHEMBL3905508) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)CC(N)=O)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H25Cl2FN6O3/c1-17(24-4-2-3-11-35-24)36-30(42)28-22-16-38(27(41)14-26(34)40)15-19(12-18-5-8-21(33)9-6-18)29(22)39(37-28)25-10-7-20(31)13-23(25)32/h2-13,17H,14-16H2,1H3,(H2,34,40)(H,36,42)/b19-12+/t17-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198727 (CHEMBL3905508) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)CC(N)=O)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H25Cl2FN6O3/c1-17(24-4-2-3-11-35-24)36-30(42)28-22-16-38(27(41)14-26(34)40)15-19(12-18-5-8-21(33)9-6-18)29(22)39(37-28)25-10-7-20(31)13-23(25)32/h2-13,17H,14-16H2,1H3,(H2,34,40)(H,36,42)/b19-12+/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair