BDBM50198734 CHEMBL3921605

SMILES: C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)[C@@H](O)CO)-c1ccc(Cl)cc1Cl)c1ccccc1

InChI Key: InChIKey=WJOMEJOSPBPKGI-YNXXKONLSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198734 (CHEMBL3921605) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)[C@@H](O)CO)-c1ccc(Cl)cc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C31H27Cl3N4O4/c1-18(20-5-3-2-4-6-20)35-30(41)28-24-16-37(31(42)27(40)17-39)15-21(13-19-7-9-22(32)10-8-19)29(24)38(36-28)26-12-11-23(33)14-25(26)34/h2-14,18,27,39-40H,15-17H2,1H3,(H,35,41)/b21-13+/t18-,27+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.91E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198734 (CHEMBL3921605) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)[C@@H](O)CO)-c1ccc(Cl)cc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C31H27Cl3N4O4/c1-18(20-5-3-2-4-6-20)35-30(41)28-24-16-37(31(42)27(40)17-39)15-21(13-19-7-9-22(32)10-8-19)29(24)38(36-28)26-12-11-23(33)14-25(26)34/h2-14,18,27,39-40H,15-17H2,1H3,(H,35,41)/b21-13+/t18-,27+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair