BDBM50198743 CHEMBL3893586

SMILES: COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)Cn2ccnc2)cc1

InChI Key: InChIKey=YTPBKNZXOGXDKV-NJRDNMGOSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198743   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198743 (CHEMBL3893586) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)Cn2ccnc2)cc1 |r| Show InChI InChI=1S/C34H30Cl2N6O3/c1-22(24-6-4-3-5-7-24)38-34(44)32-28-19-41(31(43)20-40-15-14-37-21-40)18-25(16-23-8-11-27(45-2)12-9-23)33(28)42(39-32)30-13-10-26(35)17-29(30)36/h3-17,21-22H,18-20H2,1-2H3,(H,38,44)/b25-16+/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198743 (CHEMBL3893586) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)Cn2ccnc2)cc1 |r| Show InChI InChI=1S/C34H30Cl2N6O3/c1-22(24-6-4-3-5-7-24)38-34(44)32-28-19-41(31(43)20-40-15-14-37-21-40)18-25(16-23-8-11-27(45-2)12-9-23)33(28)42(39-32)30-13-10-26(35)17-29(30)36/h3-17,21-22H,18-20H2,1-2H3,(H,38,44)/b25-16+/t22-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair