BDBM50198788 CHEMBL231235::N-(4-(7-(2,6-dimethylphenyl)-5-methylbenzo[e][1,2,4]triazin-3-ylamino)phenyl)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide

SMILES: Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(cc3)N(CCN3CCCC3)C(=O)c3ccccc3)nnc2c1

InChI Key: InChIKey=BOTCEXZBULNTQA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198788   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198788 (CHEMBL231235 | N-(4-(7-(2,6-dimethylphenyl)-5-meth...) Show SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(cc3)N(CCN3CCCC3)C(=O)c3ccccc3)nnc2c1 Show InChI InChI=1S/C35H36N6O/c1-24-10-9-11-25(2)32(24)28-22-26(3)33-31(23-28)38-39-35(37-33)36-29-14-16-30(17-15-29)41(21-20-40-18-7-8-19-40)34(42)27-12-5-4-6-13-27/h4-6,9-17,22-23H,7-8,18-21H2,1-3H3,(H,36,37,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of Src				Bioorg Med Chem Lett 17: 602-8 (2007) Article DOI: 10.1016/j.bmcl.2006.11.006 BindingDB Entry DOI: 10.7270/Q29024MW
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