BDBM50198801 4-(6-methyl-7-phenylbenzo[e][1,2,4]triazin-3-ylamino)-N-(2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide::CHEMBL230918::US8481536, 432

SMILES: Cc1cc2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2cc1-c1ccccc1

InChI Key: InChIKey=NZOQKOSNMMQJED-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198801   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198801 (4-(6-methyl-7-phenylbenzo[e][1,2,4]triazin-3-ylami...) Show SMILES Cc1cc2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2cc1-c1ccccc1 Show InChI InChI=1S/C26H28N6O2S/c1-19-17-24-25(18-23(19)20-7-3-2-4-8-20)30-31-26(29-24)28-21-9-11-22(12-10-21)35(33,34)27-13-16-32-14-5-6-15-32/h2-4,7-12,17-18,27H,5-6,13-16H2,1H3,(H,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of Src				Bioorg Med Chem Lett 17: 602-8 (2007) Article DOI: 10.1016/j.bmcl.2006.11.006 BindingDB Entry DOI: 10.7270/Q29024MW
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198801 (4-(6-methyl-7-phenylbenzo[e][1,2,4]triazin-3-ylami...) Show SMILES Cc1cc2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2cc1-c1ccccc1 Show InChI InChI=1S/C26H28N6O2S/c1-19-17-24-25(18-23(19)20-7-3-2-4-8-20)30-31-26(29-24)28-21-9-11-22(12-10-21)35(33,34)27-13-16-32-14-5-6-15-32/h2-4,7-12,17-18,27H,5-6,13-16H2,1H3,(H,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair