BDBM50198809 4-(6-methyl-7-(2-(trifluoromethyl)phenyl)benzo[e][1,2,4]triazin-3-ylamino)-N-(2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide::CHEMBL231338::US8481536, 447

SMILES: Cc1cc2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2cc1-c1ccccc1C(F)(F)F

InChI Key: InChIKey=FDDHJANHSBOLPP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198809 (4-(6-methyl-7-(2-(trifluoromethyl)phenyl)benzo[e][...) Show SMILES Cc1cc2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2cc1-c1ccccc1C(F)(F)F Show InChI InChI=1S/C27H27F3N6O2S/c1-18-16-24-25(17-22(18)21-6-2-3-7-23(21)27(28,29)30)34-35-26(33-24)32-19-8-10-20(11-9-19)39(37,38)31-12-15-36-13-4-5-14-36/h2-3,6-11,16-17,31H,4-5,12-15H2,1H3,(H,32,33,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of Src				Bioorg Med Chem Lett 17: 602-8 (2007) Article DOI: 10.1016/j.bmcl.2006.11.006 BindingDB Entry DOI: 10.7270/Q29024MW
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198809 (4-(6-methyl-7-(2-(trifluoromethyl)phenyl)benzo[e][...) Show SMILES Cc1cc2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2cc1-c1ccccc1C(F)(F)F Show InChI InChI=1S/C27H27F3N6O2S/c1-18-16-24-25(17-22(18)21-6-2-3-7-23(21)27(28,29)30)34-35-26(33-24)32-19-8-10-20(11-9-19)39(37,38)31-12-15-36-13-4-5-14-36/h2-3,6-11,16-17,31H,4-5,12-15H2,1H3,(H,32,33,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	66.5	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair