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SMILES: CN1CCN(CC1)NC(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)cc1

InChI Key: InChIKey=JWNSXXDXAWRFHJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198825   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50198825
PNG
(4-(7-(2,6-dimethylphenyl)-5-methylbenzo[e][1,2,4]t...)
Show SMILES CN1CCN(CC1)NC(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)cc1
Show InChI InChI=1S/C28H31N7O/c1-18-6-5-7-19(2)25(18)22-16-20(3)26-24(17-22)31-32-28(30-26)29-23-10-8-21(9-11-23)27(36)33-35-14-12-34(4)13-15-35/h5-11,16-17H,12-15H2,1-4H3,(H,33,36)(H,29,30,32)
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PubMed
n/an/a 15n/an/an/an/an/an/a



TargeGen, Inc.

Curated by ChEMBL


Assay Description
Inhibition of Src

Bioorg Med Chem Lett 17: 602-8 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.006
BindingDB Entry DOI: 10.7270/Q29024MW
More data for this
Ligand-Target Pair