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SMILES: CC1CCCN(C1)C(=O)C(CCn1cccc1C#N)NS(=O)(=O)c1cccc2[nH]ccc12

InChI Key: InChIKey=OXINRFPNXQUUAW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199000   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 10


(Homo sapiens (Human))		BDBM50199000
PNG
(CHEMBL3890608)
Show SMILES CC1CCCN(C1)C(=O)C(CCn1cccc1C#N)NS(=O)(=O)c1cccc2[nH]ccc12
Show InChI InChI=1S/C23H27N5O3S/c1-17-5-3-13-28(16-17)23(29)21(10-14-27-12-4-6-18(27)15-24)26-32(30,31)22-8-2-7-20-19(22)9-11-25-20/h2,4,6-9,11-12,17,21,25-26H,3,5,10,13-14,16H2,1H3
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 63n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human CCR10 expressed in CHOK1 cells coexpressing aequorin/Galphaq assessed as inhibition of human CCL27-dependent calcium flu...

Bioorg Med Chem Lett 26: 5277-5283 (2016)


Article DOI: 10.1016/j.bmcl.2016.09.047
BindingDB Entry DOI: 10.7270/Q2KD20WF
More data for this
Ligand-Target Pair