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SMILES: CC1CCN(CC1)C(=O)C(CCn1cccc1)NS(=O)(=O)c1cc(Cl)c(N)c(Cl)c1

InChI Key: InChIKey=RVJBPCUWQVZYTR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199019   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 10


(Homo sapiens (Human))		BDBM50199019
PNG
(CHEMBL3940706)
Show SMILES CC1CCN(CC1)C(=O)C(CCn1cccc1)NS(=O)(=O)c1cc(Cl)c(N)c(Cl)c1
Show InChI InChI=1S/C20H26Cl2N4O3S/c1-14-4-10-26(11-5-14)20(27)18(6-9-25-7-2-3-8-25)24-30(28,29)15-12-16(21)19(23)17(22)13-15/h2-3,7-8,12-14,18,24H,4-6,9-11,23H2,1H3
UniProtKB/SwissProt

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Similars
Article
PubMed
n/an/a 3.98E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human CCR10 expressed in CHOK1 cells coexpressing aequorin/Galphaq assessed as inhibition of human CCL27-dependent calcium flu...

Bioorg Med Chem Lett 26: 5277-5283 (2016)


Article DOI: 10.1016/j.bmcl.2016.09.047
BindingDB Entry DOI: 10.7270/Q2KD20WF
More data for this
Ligand-Target Pair