null

SMILES: COc1ccc2c(NC[C@H](O)CO)nc(C#N)c(-c3ccccc3)c2c1

InChI Key: InChIKey=KHVLDRZIYXBOLZ-AWEZNQCLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50199062 (1-{[(2S)-2,3-dihydroxypropyl]amino}-6-methoxy-4-ph...) Show SMILES COc1ccc2c(NC[C@H](O)CO)nc(C#N)c(-c3ccccc3)c2c1 Show InChI InChI=1S/C20H19N3O3/c1-26-15-7-8-16-17(9-15)19(13-5-3-2-4-6-13)18(10-21)23-20(16)22-11-14(25)12-24/h2-9,14,24-25H,11-12H2,1H3,(H,22,23)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assay				J Med Chem 49: 6954-7 (2006) Article DOI: 10.1021/jm060927v BindingDB Entry DOI: 10.7270/Q2ST7PG7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50199062 (1-{[(2S)-2,3-dihydroxypropyl]amino}-6-methoxy-4-ph...) Show SMILES COc1ccc2c(NC[C@H](O)CO)nc(C#N)c(-c3ccccc3)c2c1 Show InChI InChI=1S/C20H19N3O3/c1-26-15-7-8-16-17(9-15)19(13-5-3-2-4-6-13)18(10-21)23-20(16)22-11-14(25)12-24/h2-9,14,24-25H,11-12H2,1H3,(H,22,23)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to hERG potassium channel				J Med Chem 49: 6954-7 (2006) Article DOI: 10.1021/jm060927v BindingDB Entry DOI: 10.7270/Q2ST7PG7
					More data for this Ligand-Target Pair