BDBM50199065 3-((dimethylamino)methyl)-6-methoxy-2-methyl-4-phenylisoquinolin-1(2H)-one::CHEMBL214742

SMILES: COc1ccc2c(c1)c(-c1ccccc1)c(CN(C)C)n(C)c2=O

InChI Key: InChIKey=LLVZWOQXOBNOLZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50199065 (3-((dimethylamino)methyl)-6-methoxy-2-methyl-4-phe...) Show SMILES COc1ccc2c(c1)c(-c1ccccc1)c(CN(C)C)n(C)c2=O Show InChI InChI=1S/C20H22N2O2/c1-21(2)13-18-19(14-8-6-5-7-9-14)17-12-15(24-4)10-11-16(17)20(23)22(18)3/h5-12H,13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to hERG potassium channel				J Med Chem 49: 6954-7 (2006) Article DOI: 10.1021/jm060927v BindingDB Entry DOI: 10.7270/Q2ST7PG7
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50199065 (3-((dimethylamino)methyl)-6-methoxy-2-methyl-4-phe...) Show SMILES COc1ccc2c(c1)c(-c1ccccc1)c(CN(C)C)n(C)c2=O Show InChI InChI=1S/C20H22N2O2/c1-21(2)13-18-19(14-8-6-5-7-9-14)17-12-15(24-4)10-11-16(17)20(23)22(18)3/h5-12H,13H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assay				J Med Chem 49: 6954-7 (2006) Article DOI: 10.1021/jm060927v BindingDB Entry DOI: 10.7270/Q2ST7PG7
					More data for this Ligand-Target Pair