null

SMILES: COc1ccc2c(OC[C@H](O)CO)nc(C#N)c(-c3ccccc3)c2c1

InChI Key: InChIKey=LPNVADCXMPWFQC-CQSZACIVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50199066 (1-{[(2R)-2,3-dihydroxypropyl]oxy}-6-methoxy-4-phen...) Show SMILES COc1ccc2c(OC[C@H](O)CO)nc(C#N)c(-c3ccccc3)c2c1 Show InChI InChI=1S/C20H18N2O4/c1-25-15-7-8-16-17(9-15)19(13-5-3-2-4-6-13)18(10-21)22-20(16)26-12-14(24)11-23/h2-9,14,23-24H,11-12H2,1H3/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assay				J Med Chem 49: 6954-7 (2006) Article DOI: 10.1021/jm060927v BindingDB Entry DOI: 10.7270/Q2ST7PG7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50199066 (1-{[(2R)-2,3-dihydroxypropyl]oxy}-6-methoxy-4-phen...) Show SMILES COc1ccc2c(OC[C@H](O)CO)nc(C#N)c(-c3ccccc3)c2c1 Show InChI InChI=1S/C20H18N2O4/c1-25-15-7-8-16-17(9-15)19(13-5-3-2-4-6-13)18(10-21)22-20(16)26-12-14(24)11-23/h2-9,14,23-24H,11-12H2,1H3/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to hERG potassium channel				J Med Chem 49: 6954-7 (2006) Article DOI: 10.1021/jm060927v BindingDB Entry DOI: 10.7270/Q2ST7PG7
					More data for this Ligand-Target Pair