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BDBM50199079 CHEMBL3944089

SMILES: CC1CCN(CC1)C(=O)C(CCn1ccnc1)NS(=O)(=O)c1cc(Cl)c(N)c(Cl)c1

InChI Key: InChIKey=TXCJGZQGRIXSLW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199079   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 10


(Homo sapiens (Human))		BDBM50199079
PNG
(CHEMBL3944089)
Show SMILES CC1CCN(CC1)C(=O)C(CCn1ccnc1)NS(=O)(=O)c1cc(Cl)c(N)c(Cl)c1
Show InChI InChI=1S/C19H25Cl2N5O3S/c1-13-2-7-26(8-3-13)19(27)17(4-6-25-9-5-23-12-25)24-30(28,29)14-10-15(20)18(22)16(21)11-14/h5,9-13,17,24H,2-4,6-8,22H2,1H3
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a<2.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human CCR10 expressed in CHOK1 cells coexpressing aequorin/Galphaq assessed as inhibition of CCL27-dependent calcium flux in p...

Bioorg Med Chem Lett 26: 5277-5283 (2016)


Article DOI: 10.1016/j.bmcl.2016.09.047
BindingDB Entry DOI: 10.7270/Q2KD20WF
More data for this
Ligand-Target Pair