BDBM50199326 CHEMBL217673::N-butyloxycarbonyl-2-(4-imidazol-1-ylmethylphenyl)-4-iso-butylbenzenesulfonamide
SMILES: CCCCOC(=O)NS(=O)(=O)c1ccc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1
InChI Key: InChIKey=IEKPELSFCDOQBA-UHFFFAOYSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Angiotensin II receptor (Homo sapiens (Human)) | BDBM50199326 (CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane | J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin II receptor (Homo sapiens (Human)) | BDBM50199326 (CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity to type-2 angiotensin-2 receptor (unknown origin) | Bioorg Med Chem Lett 26: 1355-9 (2016) BindingDB Entry DOI: 10.7270/Q2SN0BT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin II receptor (Homo sapiens (Human)) | BDBM50199326 (CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins... | J Med Chem 59: 810-40 (2016) BindingDB Entry DOI: 10.7270/Q2XS5X8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Sus scrofa) | BDBM50199326 (CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane | Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin II AT2 (RAT) | BDBM50199326 (CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane | J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AGTR1 (RAT) | BDBM50199326 (CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [125]Ang2 from AT1 receptor in rat liver membrane | Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C | |||||||||||
More data for this Ligand-Target Pair |