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SMILES: COc1cc(N2CC[C@H](C2)N(C)C)c2nc(cc(O)c2c1)C(=O)Nc1ccc(cc1)N1CCOCC1

InChI Key: InChIKey=CYIRKLFDCHLBJQ-HXUWFJFHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199559   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50199559
PNG
(8-((3R)-(+)-3-dimethylamino-pyrrolidin-1-yl)-6-met...)
Show SMILES COc1cc(N2CC[C@H](C2)N(C)C)c2nc(cc(O)c2c1)C(=O)Nc1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C27H33N5O4/c1-30(2)20-8-9-32(17-20)24-15-21(35-3)14-22-25(33)16-23(29-26(22)24)27(34)28-18-4-6-19(7-5-18)31-10-12-36-13-11-31/h4-7,14-16,20H,8-13,17H2,1-3H3,(H,28,34)(H,29,33)/t20-/m1/s1
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Article
PubMed
 35n/an/an/an/an/an/an/an/a



AstraZeneca Pharmaceuticals LP

Curated by ChEMBL


Assay Description
Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cells

Bioorg Med Chem 15: 939-50 (2006)


Article DOI: 10.1016/j.bmc.2006.10.037
BindingDB Entry DOI: 10.7270/Q2445M3X
More data for this
Ligand-Target Pair