BDBM50200002 CHEMBL3959992

SMILES: COc1ccc(cc1S(=O)(=O)n1cccn1)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12

InChI Key: InChIKey=UUSQIPCGWYYEAK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50200002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200002 (CHEMBL3959992) Show SMILES COc1ccc(cc1S(=O)(=O)n1cccn1)-c1c(C)nc2c(NCCNC(C)=O)cc(Cl)nn12 Show InChI InChI=1S/C21H22ClN7O4S/c1-13-20(29-21(26-13)16(12-19(22)27-29)24-9-8-23-14(2)30)15-5-6-17(33-3)18(11-15)34(31,32)28-10-4-7-25-28/h4-7,10-12,24H,8-9H2,1-3H3,(H,23,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of PI4KB (unknown origin) by ADP-Glo kinase assay				J Med Chem 60: 100-118 (2017) Article DOI: 10.1021/acs.jmedchem.6b01465 BindingDB Entry DOI: 10.7270/Q28054K8
					More data for this Ligand-Target Pair