BDBM50200107 CHEMBL3963020

SMILES: CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)NCc2cn(nn2)-c2cc3ccc(O)cc3oc2=O)ccn1

InChI Key: InChIKey=GUTXDQHXXXMWDW-UHFFFAOYSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200107 (CHEMBL3963020) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)NCc2cn(nn2)-c2cc3ccc(O)cc3oc2=O)ccn1 Show InChI InChI=1S/C34H30ClN9O6S/c1-4-23-11-20(9-10-36-23)16-37-26-15-31(35)41-44-32(19(2)39-33(26)44)22-6-8-28(49-3)30(13-22)51(47,48)38-17-24-18-43(42-40-24)27-12-21-5-7-25(45)14-29(21)50-34(27)46/h5-15,18,37-38,45H,4,16-17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of 6xHisGB1 tagged PI4KB (unknown origin) expressed in Escherichia coli BL21 Star				J Med Chem 60: 119-127 (2017) Article DOI: 10.1021/acs.jmedchem.6b01466 BindingDB Entry DOI: 10.7270/Q2474CVJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50200107 (CHEMBL3963020) Show SMILES CCc1cc(CNc2cc(Cl)nn3c(c(C)nc23)-c2ccc(OC)c(c2)S(=O)(=O)NCc2cn(nn2)-c2cc3ccc(O)cc3oc2=O)ccn1 Show InChI InChI=1S/C34H30ClN9O6S/c1-4-23-11-20(9-10-36-23)16-37-26-15-31(35)41-44-32(19(2)39-33(26)44)22-6-8-28(49-3)30(13-22)51(47,48)38-17-24-18-43(42-40-24)27-12-21-5-7-25(45)14-29(21)50-34(27)46/h5-15,18,37-38,45H,4,16-17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Binding affinity to 6xHisGB1 tagged PI4KB (unknown origin) expressed in Escherichia coli BL21 Star by fluorescence anisotropy based method				J Med Chem 60: 119-127 (2017) Article DOI: 10.1021/acs.jmedchem.6b01466 BindingDB Entry DOI: 10.7270/Q2474CVJ
					More data for this Ligand-Target Pair