BDBM50200189 (S)-2-amino-N-hydroxy-3-[4-(nitrophenyl)phenyl]propanamide::CHEMBL219449

SMILES: N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)[N+]([O-])=O)C(=O)NO

InChI Key: InChIKey=YAAKBFZQPSYWDN-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50200189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase CSK (Homo sapiens (Human))	BDBM50200189 ((S)-2-amino-N-hydroxy-3-[4-(nitrophenyl)phenyl]pro...) Show SMILES N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)[N+]([O-])=O)C(=O)NO |r| Show InChI InChI=1S/C15H15N3O4/c16-14(15(19)17-20)9-10-1-3-11(4-2-10)12-5-7-13(8-6-12)18(21)22/h1-8,14,20H,9,16H2,(H,17,19)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Rhode Island Curated by ChEMBL					Assay Description Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2				J Med Chem 49: 7532-9 (2006) Article DOI: 10.1021/jm061058c BindingDB Entry DOI: 10.7270/Q2SQ9029
					More data for this Ligand-Target Pair