BDBM50200197 (S)-2-amino-N-hydroxy-3-(4-hydroxyphenyl)propanethioamide::CHEMBL425977

SMILES: N[C@@H](Cc1ccc(O)cc1)C(=S)NO

InChI Key: InChIKey=SEXRDSAWPZOSJN-QMMMGPOBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50200197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase CSK (Homo sapiens (Human))	BDBM50200197 ((S)-2-amino-N-hydroxy-3-(4-hydroxyphenyl)propaneth...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=S)NO |r| Show InChI InChI=1S/C9H12N2O2S/c10-8(9(14)11-13)5-6-1-3-7(12)4-2-6/h1-4,8,12-13H,5,10H2,(H,11,14)/t8-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Rhode Island Curated by ChEMBL					Assay Description Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2				J Med Chem 49: 7532-9 (2006) Article DOI: 10.1021/jm061058c BindingDB Entry DOI: 10.7270/Q2SQ9029
					More data for this Ligand-Target Pair