BDBM50200266 4-bromo-2-[1-(4-chlorophenyl)-1H-pyrazole-4-carbonyl]phenoxyacetic acid::CHEMBL217393

SMILES: OC(=O)COc1ccc(Br)cc1C(=O)c1cnn(c1)-c1ccc(Cl)cc1

InChI Key: InChIKey=BFDKWNZBUIDXIV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200266   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50200266 (4-bromo-2-[1-(4-chlorophenyl)-1H-pyrazole-4-carbon...) Show SMILES OC(=O)COc1ccc(Br)cc1C(=O)c1cnn(c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H12BrClN2O4/c19-12-1-6-16(26-10-17(23)24)15(7-12)18(25)11-8-21-22(9-11)14-4-2-13(20)3-5-14/h1-9H,10H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells				J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50200266 (4-bromo-2-[1-(4-chlorophenyl)-1H-pyrazole-4-carbon...) Show SMILES OC(=O)COc1ccc(Br)cc1C(=O)c1cnn(c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H12BrClN2O4/c19-12-1-6-16(26-10-17(23)24)15(7-12)18(25)11-8-21-22(9-11)14-4-2-13(20)3-5-14/h1-9H,10H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma Curated by ChEMBL					Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay				J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0
					More data for this Ligand-Target Pair