null
SMILES: Brc1cccc(Nc2ncnc3ccc(NC(=O)CC4CCSS4)cc23)c1
InChI Key: InChIKey=MFUUYCMEELSIJK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50200278 (CHEMBL450944 | N-(4-(3-bromophenylamino)quinazolin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Inhibition of EGFR tyrosine kinase activity | J Med Chem 49: 6642-5 (2006) Article DOI: 10.1021/jm0608762 BindingDB Entry DOI: 10.7270/Q28P605H | |||||||||||
More data for this Ligand-Target Pair |