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SMILES: Brc1cccc(Nc2ncnc3ccc(NC(=O)C4CCSS4)cc23)c1

InChI Key: InChIKey=LMKVUAKMZVPHNQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50200279   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50200279
PNG
(CHEMBL217536 | N-(4-(3-bromophenylamino)quinazolin...)
Show SMILES Brc1cccc(Nc2ncnc3ccc(NC(=O)C4CCSS4)cc23)c1
Show InChI InChI=1S/C18H15BrN4OS2/c19-11-2-1-3-12(8-11)22-17-14-9-13(4-5-15(14)20-10-21-17)23-18(24)16-6-7-25-26-16/h1-5,8-10,16H,6-7H2,(H,23,24)(H,20,21,22)
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KEGG

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Similars
Article
PubMed
n/an/a 60n/an/an/an/an/an/a



University of Bologna

Curated by ChEMBL


Assay Description
Inhibition of EGFR tyrosine kinase activity

J Med Chem 49: 6642-5 (2006)


Article DOI: 10.1021/jm0608762
BindingDB Entry DOI: 10.7270/Q28P605H
More data for this
Ligand-Target Pair