BindingDB PrimarySearch

BDBM50200403 (S)-2-(5-(3-((2-(4-isopropylphenyl)-5-methylpyrimidin-4-yl)(methyl)amino)propoxy)-2,3-dihydro-1H-inden-1-yl)acetic acid::CHEMBL239353

SMILES: CC(C)c1ccc(cc1)-c1ncc(C)c(n1)N(C)CCCOc1ccc2[C@H](CC(O)=O)CCc2c1

InChI Key: InChIKey=VAXBUDASTPYURF-DEOSSOPVSA-N

Data: 4 IC50 3 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50200403
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Mus musculus)	BDBM50200403 ((S)-2-(5-(3-((2-(4-isopropylphenyl)-5-methylpyrimi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Agonist activity at PPARgamma in mouse 3T3-L1 cells by IRBA				Bioorg Med Chem Lett 17: 1056-61 (2007) Article DOI: 10.1016/j.bmcl.2006.11.025 BindingDB Entry DOI: 10.7270/Q2CF9PR2
Bayer Pharmaceuticals Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mus musculus)	BDBM50200403 ((S)-2-(5-(3-((2-(4-isopropylphenyl)-5-methylpyrimi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Activity at mouse PPARalpha expressed in CV1 cells by GAL4 transactivation assay				Bioorg Med Chem Lett 17: 1056-61 (2007) Article DOI: 10.1016/j.bmcl.2006.11.025 BindingDB Entry DOI: 10.7270/Q2CF9PR2
Bayer Pharmaceuticals Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50200403 ((S)-2-(5-(3-((2-(4-isopropylphenyl)-5-methylpyrimi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Activity at human PPARalpha expressed in CV1 cells by GAL4 transactivation assay				Bioorg Med Chem Lett 17: 1056-61 (2007) Article DOI: 10.1016/j.bmcl.2006.11.025 BindingDB Entry DOI: 10.7270/Q2CF9PR2
Bayer Pharmaceuticals Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Mus musculus)	BDBM50200403 ((S)-2-(5-(3-((2-(4-isopropylphenyl)-5-methylpyrimi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Activity at mouse PPARdelta expressed in CV1 cells by GAL4 transactivation assay				Bioorg Med Chem Lett 17: 1056-61 (2007) Article DOI: 10.1016/j.bmcl.2006.11.025 BindingDB Entry DOI: 10.7270/Q2CF9PR2
Bayer Pharmaceuticals Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50200403 ((S)-2-(5-(3-((2-(4-isopropylphenyl)-5-methylpyrimi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta by FRET assay				Bioorg Med Chem Lett 17: 1056-61 (2007) Article DOI: 10.1016/j.bmcl.2006.11.025 BindingDB Entry DOI: 10.7270/Q2CF9PR2
Bayer Pharmaceuticals Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50200403 ((S)-2-(5-(3-((2-(4-isopropylphenyl)-5-methylpyrimi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	990	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha by FRET assay				Bioorg Med Chem Lett 17: 1056-61 (2007) Article DOI: 10.1016/j.bmcl.2006.11.025 BindingDB Entry DOI: 10.7270/Q2CF9PR2
Bayer Pharmaceuticals Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50200403 ((S)-2-(5-(3-((2-(4-isopropylphenyl)-5-methylpyrimi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Activity at human PPARdelta expressed in CV1 cells by GAL4 transactivation assay				Bioorg Med Chem Lett 17: 1056-61 (2007) Article DOI: 10.1016/j.bmcl.2006.11.025 BindingDB Entry DOI: 10.7270/Q2CF9PR2
Bayer Pharmaceuticals Corporation Curated by ChEMBL					More data for this Ligand-Target Pair