BDBM50200439 CHEMBL3917847

SMILES: COc1cccc(Nc2n[nH]c3CCN(Cc23)C(C)=O)c1

InChI Key: InChIKey=UUBWOQFEIRJDKR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CREB-binding protein/Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50200439 (CHEMBL3917847) Show SMILES COc1cccc(Nc2n[nH]c3CCN(Cc23)C(C)=O)c1 Show InChI InChI=1S/C15H18N4O2/c1-10(20)19-7-6-14-13(9-19)15(18-17-14)16-11-4-3-5-12(8-11)21-2/h3-5,8H,6-7,9H2,1-2H3,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Displacement of biotinylated ligand from recombinant His-tagged CBP/EP300 (unknown origin) measured after 10 mins by TR-FRET assay				J Med Chem 59: 10549-10563 (2016) Article DOI: 10.1021/acs.jmedchem.6b01022 BindingDB Entry DOI: 10.7270/Q27083DF
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50200439 (CHEMBL3917847) Show SMILES COc1cccc(Nc2n[nH]c3CCN(Cc23)C(C)=O)c1 Show InChI InChI=1S/C15H18N4O2/c1-10(20)19-7-6-14-13(9-19)15(18-17-14)16-11-4-3-5-12(8-11)21-2/h3-5,8H,6-7,9H2,1-2H3,(H2,16,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Displacement of biotinylated ligand from recombinant His-tagged BRD4 bromodomain-1 (unknown origin) measured after 10 mins by TR-FRET assay				J Med Chem 59: 10549-10563 (2016) Article DOI: 10.1021/acs.jmedchem.6b01022 BindingDB Entry DOI: 10.7270/Q27083DF
					More data for this Ligand-Target Pair