Found 13 hits for monomerid = 50200534 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant KDR (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant ABL (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Kit (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant wild type ALK (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
1,3-beta-glucan synthase component GLS2
(Saccharomyces cerevisiae) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant PDGFR-alpha (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant EGFR (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant ErbB2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Src (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
Ephrin type-A receptor 2
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant EPHA2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant PDGFR-beta (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
Receptor protein-tyrosine kinase erbB-4
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant ErbB4 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |
Insulin-like growth factor I receptor
(Homo sapiens (Human)) | BDBM50200534
(CHEMBL3958173)Show SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-4-21-16-23-24(17-26(21)35-11-9-34(10-12-35)19-31(37)7-13-38-14-8-31)30(2,3)29-27(28(23)36)22-6-5-20(18-32)15-25(22)33-29/h5-6,15-17,33,37H,4,7-14,19H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China
Curated by ChEMBL
| Assay Description Inhibition of recombinant IGF1R (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA |
Bioorg Med Chem Lett 26: 5399-5402 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW |
More data for this Ligand-Target Pair | |