BDBM50200596 CHEMBL240085::N-ethyl-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-2-oxo-2,3-dihydrobenzimidazol-1-yl)-acetamide

SMILES: CCNC(=O)Cn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O

InChI Key: InChIKey=MTTZPKNMSDFTCL-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50200596 (CHEMBL240085 | N-ethyl-2-(3-{1-[3-(5-methoxy-2-met...) Show SMILES CCNC(=O)Cn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:20.21| Show InChI InChI=1S/C30H42N4O4/c1-6-31-29(35)20-33-25-9-7-8-10-26(25)34(30(33)36)23-13-16-32(17-14-23)18-15-27(21(2)3)38-28-19-24(37-5)12-11-22(28)4/h7-12,19,21,23,27H,6,13-18,20H2,1-5H3,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cells				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50200596 (CHEMBL240085 | N-ethyl-2-(3-{1-[3-(5-methoxy-2-met...) Show SMILES CCNC(=O)Cn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:20.21| Show InChI InChI=1S/C30H42N4O4/c1-6-31-29(35)20-33-25-9-7-8-10-26(25)34(30(33)36)23-13-16-32(17-14-23)18-15-27(21(2)3)38-28-19-24(37-5)12-11-22(28)4/h7-12,19,21,23,27H,6,13-18,20H2,1-5H3,(H,31,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	289	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cells				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50200596 (CHEMBL240085 | N-ethyl-2-(3-{1-[3-(5-methoxy-2-met...) Show SMILES CCNC(=O)Cn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:20.21| Show InChI InChI=1S/C30H42N4O4/c1-6-31-29(35)20-33-25-9-7-8-10-26(25)34(30(33)36)23-13-16-32(17-14-23)18-15-27(21(2)3)38-28-19-24(37-5)12-11-22(28)4/h7-12,19,21,23,27H,6,13-18,20H2,1-5H3,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrs				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair