BDBM50200600 (+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one::(-)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one::1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one::CHEMBL238833

SMILES: COCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O

InChI Key: InChIKey=HODPFCFYQOZXPB-UHFFFAOYSA-N

Data: 6 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50200600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50200600 ((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...) Show SMILES COCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:17.18| Show InChI InChI=1S/C28H39N3O4/c1-20(2)26(35-27-18-23(34-5)11-10-21(27)3)14-17-29-15-12-22(13-16-29)31-25-9-7-6-8-24(25)30(19-33-4)28(31)32/h6-11,18,20,22,26H,12-17,19H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cells				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50200600 ((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...) Show SMILES COCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:17.18| Show InChI InChI=1S/C28H39N3O4/c1-20(2)26(35-27-18-23(34-5)11-10-21(27)3)14-17-29-15-12-22(13-16-29)31-25-9-7-6-8-24(25)30(19-33-4)28(31)32/h6-11,18,20,22,26H,12-17,19H2,1-5H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cells				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50200600 ((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...) Show SMILES COCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:17.18| Show InChI InChI=1S/C28H39N3O4/c1-20(2)26(35-27-18-23(34-5)11-10-21(27)3)14-17-29-15-12-22(13-16-29)31-25-9-7-6-8-24(25)30(19-33-4)28(31)32/h6-11,18,20,22,26H,12-17,19H2,1-5H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cells				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50200600 ((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...) Show SMILES COCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:17.18| Show InChI InChI=1S/C28H39N3O4/c1-20(2)26(35-27-18-23(34-5)11-10-21(27)3)14-17-29-15-12-22(13-16-29)31-25-9-7-6-8-24(25)30(19-33-4)28(31)32/h6-11,18,20,22,26H,12-17,19H2,1-5H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissue				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50200600 ((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...) Show SMILES COCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:17.18| Show InChI InChI=1S/C28H39N3O4/c1-20(2)26(35-27-18-23(34-5)11-10-21(27)3)14-17-29-15-12-22(13-16-29)31-25-9-7-6-8-24(25)30(19-33-4)28(31)32/h6-11,18,20,22,26H,12-17,19H2,1-5H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissue				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50200600 ((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...) Show SMILES COCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:17.18| Show InChI InChI=1S/C28H39N3O4/c1-20(2)26(35-27-18-23(34-5)11-10-21(27)3)14-17-29-15-12-22(13-16-29)31-25-9-7-6-8-24(25)30(19-33-4)28(31)32/h6-11,18,20,22,26H,12-17,19H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]naltrindole from human DOP receptor expressed in deltaC6 cells				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50200600 ((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...) Show SMILES COCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:17.18| Show InChI InChI=1S/C28H39N3O4/c1-20(2)26(35-27-18-23(34-5)11-10-21(27)3)14-17-29-15-12-22(13-16-29)31-25-9-7-6-8-24(25)30(19-33-4)28(31)32/h6-11,18,20,22,26H,12-17,19H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrs				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50200600 ((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...) Show SMILES COCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:17.18| Show InChI InChI=1S/C28H39N3O4/c1-20(2)26(35-27-18-23(34-5)11-10-21(27)3)14-17-29-15-12-22(13-16-29)31-25-9-7-6-8-24(25)30(19-33-4)28(31)32/h6-11,18,20,22,26H,12-17,19H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrs				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair