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SMILES: C[C@@H]1CN(Cc2ccccc2F)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1

InChI Key: InChIKey=SIFUDDZFIOEDIJ-MOPGFXCFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1I (Homo sapiens (Human))	BDBM50200857 (CHEMBL3972450) Show SMILES C[C@@H]1CN(Cc2ccccc2F)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C25H27FN4O/c1-18-16-29(17-21-10-6-7-11-23(21)26)24-15-27-13-12-22(24)19(2)30(18)25(31)28-14-20-8-4-3-5-9-20/h3-13,15,18-19H,14,16-17H2,1-2H3,(H,28,31)/t18-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.3 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50200857 (CHEMBL3972450) Show SMILES C[C@@H]1CN(Cc2ccccc2F)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C25H27FN4O/c1-18-16-29(17-21-10-6-7-11-23(21)26)24-15-27-13-12-22(24)19(2)30(18)25(31)28-14-20-8-4-3-5-9-20/h3-13,15,18-19H,14,16-17H2,1-2H3,(H,28,31)/t18-,19+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50200857 (CHEMBL3972450) Show SMILES C[C@@H]1CN(Cc2ccccc2F)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C25H27FN4O/c1-18-16-29(17-21-10-6-7-11-23(21)26)24-15-27-13-12-22(24)19(2)30(18)25(31)28-14-20-8-4-3-5-9-20/h3-13,15,18-19H,14,16-17H2,1-2H3,(H,28,31)/t18-,19+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair