BDBM50200904 CHEMBL3936835

SMILES: C[C@@H]1CN(Cc2ccccc2)c2cc(F)ccc2[C@H](C)N1C(=O)Nc1cccnc1

InChI Key: InChIKey=DKIVTKARIWZZCD-MSOLQXFVSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50200904 (CHEMBL3936835) Show SMILES C[C@@H]1CN(Cc2ccccc2)c2cc(F)ccc2[C@H](C)N1C(=O)Nc1cccnc1 |r| Show InChI InChI=1S/C24H25FN4O/c1-17-15-28(16-19-7-4-3-5-8-19)23-13-20(25)10-11-22(23)18(2)29(17)24(30)27-21-9-6-12-26-14-21/h3-14,17-18H,15-16H2,1-2H3,(H,27,30)/t17-,18+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50200904 (CHEMBL3936835) Show SMILES C[C@@H]1CN(Cc2ccccc2)c2cc(F)ccc2[C@H](C)N1C(=O)Nc1cccnc1 |r| Show InChI InChI=1S/C24H25FN4O/c1-17-15-28(16-19-7-4-3-5-8-19)23-13-20(25)10-11-22(23)18(2)29(17)24(30)27-21-9-6-12-26-14-21/h3-14,17-18H,15-16H2,1-2H3,(H,27,30)/t17-,18+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50200904 (CHEMBL3936835) Show SMILES C[C@@H]1CN(Cc2ccccc2)c2cc(F)ccc2[C@H](C)N1C(=O)Nc1cccnc1 |r| Show InChI InChI=1S/C24H25FN4O/c1-17-15-28(16-19-7-4-3-5-8-19)23-13-20(25)10-11-22(23)18(2)29(17)24(30)27-21-9-6-12-26-14-21/h3-14,17-18H,15-16H2,1-2H3,(H,27,30)/t17-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.3 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair