BDBM50200908 CHEMBL3921940

SMILES: CC(C)CCN1C[C@@H](C)N([C@@H](C)c2c(F)cccc12)C(=O)CCc1cccnc1

InChI Key: InChIKey=GFAZKXBHWPWIIM-MOPGFXCFSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50200908 (CHEMBL3921940) Show SMILES CC(C)CCN1C[C@@H](C)N([C@@H](C)c2c(F)cccc12)C(=O)CCc1cccnc1 |r| Show InChI InChI=1S/C24H32FN3O/c1-17(2)12-14-27-16-18(3)28(19(4)24-21(25)8-5-9-22(24)27)23(29)11-10-20-7-6-13-26-15-20/h5-9,13,15,17-19H,10-12,14,16H2,1-4H3/t18-,19+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.3 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50200908 (CHEMBL3921940) Show SMILES CC(C)CCN1C[C@@H](C)N([C@@H](C)c2c(F)cccc12)C(=O)CCc1cccnc1 |r| Show InChI InChI=1S/C24H32FN3O/c1-17(2)12-14-27-16-18(3)28(19(4)24-21(25)8-5-9-22(24)27)23(29)11-10-20-7-6-13-26-15-20/h5-9,13,15,17-19H,10-12,14,16H2,1-4H3/t18-,19+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50200908 (CHEMBL3921940) Show SMILES CC(C)CCN1C[C@@H](C)N([C@@H](C)c2c(F)cccc12)C(=O)CCc1cccnc1 |r| Show InChI InChI=1S/C24H32FN3O/c1-17(2)12-14-27-16-18(3)28(19(4)24-21(25)8-5-9-22(24)27)23(29)11-10-20-7-6-13-26-15-20/h5-9,13,15,17-19H,10-12,14,16H2,1-4H3/t18-,19+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair