BDBM50200921 CHEMBL3898772

SMILES: C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NC1COC1

InChI Key: InChIKey=JJKNTWZITITEHD-SJORKVTESA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50200921 (CHEMBL3898772) Show SMILES C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NC1COC1 |r| Show InChI InChI=1S/C22H27N3O2/c1-16-12-24(13-18-8-4-3-5-9-18)21-11-7-6-10-20(21)17(2)25(16)22(26)23-19-14-27-15-19/h3-11,16-17,19H,12-15H2,1-2H3,(H,23,26)/t16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.3 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50200921 (CHEMBL3898772) Show SMILES C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NC1COC1 |r| Show InChI InChI=1S/C22H27N3O2/c1-16-12-24(13-18-8-4-3-5-9-18)21-11-7-6-10-20(21)17(2)25(16)22(26)23-19-14-27-15-19/h3-11,16-17,19H,12-15H2,1-2H3,(H,23,26)/t16-,17+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50200921 (CHEMBL3898772) Show SMILES C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NC1COC1 |r| Show InChI InChI=1S/C22H27N3O2/c1-16-12-24(13-18-8-4-3-5-9-18)21-11-7-6-10-20(21)17(2)25(16)22(26)23-19-14-27-15-19/h3-11,16-17,19H,12-15H2,1-2H3,(H,23,26)/t16-,17+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...				J Med Chem 59: 10661-10675 (2016) Article DOI: 10.1021/acs.jmedchem.6b01356 BindingDB Entry DOI: 10.7270/Q2RV0QN8
					More data for this Ligand-Target Pair