BDBM50201040 CHEMBL3935102

SMILES: CN1CCN(Cc2ccc(cc2)-c2cn3CCC[C@H](N)C(=O)NCCCCCCNc4ncc2c3n4)CC1

InChI Key: InChIKey=VNERMGVCIRNEMM-SANMLTNESA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50201040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50201040 (CHEMBL3935102) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCC[C@H](N)C(=O)NCCCCCCNc4ncc2c3n4)CC1 |r| Show InChI InChI=1S/C29H42N8O/c1-35-15-17-36(18-16-35)20-22-8-10-23(11-9-22)25-21-37-14-6-7-26(30)28(38)31-12-4-2-3-5-13-32-29-33-19-24(25)27(37)34-29/h8-11,19,21,26H,2-7,12-18,20,30H2,1H3,(H,31,38)(H,32,33,34)/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of human MerTK kinase domain (1585 to 3000 residues) expressed in HEK293 cells co-expressing rat EGFR LBD assessed as inhibition of EGF-st...				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50201040 (CHEMBL3935102) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCC[C@H](N)C(=O)NCCCCCCNc4ncc2c3n4)CC1 |r| Show InChI InChI=1S/C29H42N8O/c1-35-15-17-36(18-16-35)20-22-8-10-23(11-9-22)25-21-37-14-6-7-26(30)28(38)31-12-4-2-3-5-13-32-29-33-19-24(25)27(37)34-29/h8-11,19,21,26H,2-7,12-18,20,30H2,1H3,(H,31,38)(H,32,33,34)/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of MerTK (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50201040 (CHEMBL3935102) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCC[C@H](N)C(=O)NCCCCCCNc4ncc2c3n4)CC1 |r| Show InChI InChI=1S/C29H42N8O/c1-35-15-17-36(18-16-35)20-22-8-10-23(11-9-22)25-21-37-14-6-7-26(30)28(38)31-12-4-2-3-5-13-32-29-33-19-24(25)27(37)34-29/h8-11,19,21,26H,2-7,12-18,20,30H2,1H3,(H,31,38)(H,32,33,34)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50201040 (CHEMBL3935102) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCC[C@H](N)C(=O)NCCCCCCNc4ncc2c3n4)CC1 |r| Show InChI InChI=1S/C29H42N8O/c1-35-15-17-36(18-16-35)20-22-8-10-23(11-9-22)25-21-37-14-6-7-26(30)28(38)31-12-4-2-3-5-13-32-29-33-19-24(25)27(37)34-29/h8-11,19,21,26H,2-7,12-18,20,30H2,1H3,(H,31,38)(H,32,33,34)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro3 (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50201040 (CHEMBL3935102) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCC[C@H](N)C(=O)NCCCCCCNc4ncc2c3n4)CC1 |r| Show InChI InChI=1S/C29H42N8O/c1-35-15-17-36(18-16-35)20-22-8-10-23(11-9-22)25-21-37-14-6-7-26(30)28(38)31-12-4-2-3-5-13-32-29-33-19-24(25)27(37)34-29/h8-11,19,21,26H,2-7,12-18,20,30H2,1H3,(H,31,38)(H,32,33,34)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Flt3 (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair