BDBM50201076 CHEMBL3951096

SMILES: CN1CCN(Cc2ccc(cc2)-c2cn3CCCC(O)CCCCCNc4ncc2c3n4)CC1

InChI Key: InChIKey=SMIXLVLRWCBPBA-UHFFFAOYSA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50201076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50201076 (CHEMBL3951096) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCCC(O)CCCCCNc4ncc2c3n4)CC1 Show InChI InChI=1S/C27H38N6O/c1-31-14-16-32(17-15-31)19-21-8-10-22(11-9-21)25-20-33-13-5-7-23(34)6-3-2-4-12-28-27-29-18-24(25)26(33)30-27/h8-11,18,20,23,34H,2-7,12-17,19H2,1H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of MerTK (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50201076 (CHEMBL3951096) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCCC(O)CCCCCNc4ncc2c3n4)CC1 Show InChI InChI=1S/C27H38N6O/c1-31-14-16-32(17-15-31)19-21-8-10-22(11-9-21)25-20-33-13-5-7-23(34)6-3-2-4-12-28-27-29-18-24(25)26(33)30-27/h8-11,18,20,23,34H,2-7,12-17,19H2,1H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro3 (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50201076 (CHEMBL3951096) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCCC(O)CCCCCNc4ncc2c3n4)CC1 Show InChI InChI=1S/C27H38N6O/c1-31-14-16-32(17-15-31)19-21-8-10-22(11-9-21)25-20-33-13-5-7-23(34)6-3-2-4-12-28-27-29-18-24(25)26(33)30-27/h8-11,18,20,23,34H,2-7,12-17,19H2,1H3,(H,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50201076 (CHEMBL3951096) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCCC(O)CCCCCNc4ncc2c3n4)CC1 Show InChI InChI=1S/C27H38N6O/c1-31-14-16-32(17-15-31)19-21-8-10-22(11-9-21)25-20-33-13-5-7-23(34)6-3-2-4-12-28-27-29-18-24(25)26(33)30-27/h8-11,18,20,23,34H,2-7,12-17,19H2,1H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Flt3 (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50201076 (CHEMBL3951096) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cn3CCCC(O)CCCCCNc4ncc2c3n4)CC1 Show InChI InChI=1S/C27H38N6O/c1-31-14-16-32(17-15-31)19-21-8-10-22(11-9-21)25-20-33-13-5-7-23(34)6-3-2-4-12-28-27-29-18-24(25)26(33)30-27/h8-11,18,20,23,34H,2-7,12-17,19H2,1H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of human MerTK kinase domain (1585 to 3000 residues) expressed in HEK293 cells co-expressing rat EGFR LBD assessed as inhibition of EGF-st...				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair