BindingDB logo
myBDB logout

null

SMILES: Cc1cn(CC(O)(CC(C)(C)c2cccc3CCOc23)C(F)(F)F)cc(C)c1=O

InChI Key: InChIKey=IHRJBJXTYVYEES-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201089   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50201089
PNG
(1-[4-(2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-meth...)
Show SMILES Cc1cn(CC(O)(CC(C)(C)c2cccc3CCOc23)C(F)(F)F)cc(C)c1=O
Show InChI InChI=1S/C22H26F3NO3/c1-14-10-26(11-15(2)18(14)27)13-21(28,22(23,24)25)12-20(3,4)17-7-5-6-16-8-9-29-19(16)17/h5-7,10-11,28H,8-9,12-13H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 34n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assay

J Med Chem 49: 7887-96 (2006)


Article DOI: 10.1021/jm061273t
BindingDB Entry DOI: 10.7270/Q2BG2PTB
More data for this
Ligand-Target Pair