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SMILES: Cc1ccc(F)cc1C(C)(C)CC(O)(Cn1ccc(=O)c2cnccc12)C(F)(F)F

InChI Key: InChIKey=ZLZFWACGUPOOEK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201107   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50201107
PNG
(1-[4-(5-fluoro-2-methylphenyl)-2-hydroxy-4-methyl-...)
Show SMILES Cc1ccc(F)cc1C(C)(C)CC(O)(Cn1ccc(=O)c2cnccc12)C(F)(F)F
Show InChI InChI=1S/C22H22F4N2O2/c1-14-4-5-15(23)10-17(14)20(2,3)12-21(30,22(24,25)26)13-28-9-7-19(29)16-11-27-8-6-18(16)28/h4-11,30H,12-13H2,1-3H3
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Article
PubMed
n/an/a 48n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assay

J Med Chem 49: 7887-96 (2006)


Article DOI: 10.1021/jm061273t
BindingDB Entry DOI: 10.7270/Q2BG2PTB
More data for this
Ligand-Target Pair