Found 3 hits for monomerid = 50201127 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50201127
(3-(5-(1H-imidazol-1-yl)-7-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1ccc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C16H13N5O/c1-10-7-11(21-6-5-17-9-21)8-13-14(10)20-15(19-13)12-3-2-4-18-16(12)22/h2-9H,1H3,(H,18,22)(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of IGF1R |
Bioorg Med Chem Lett 17: 974-7 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.041 BindingDB Entry DOI: 10.7270/Q25T3K4D |
More data for this Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50201127
(3-(5-(1H-imidazol-1-yl)-7-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1ccc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C16H13N5O/c1-10-7-11(21-6-5-17-9-21)8-13-14(10)20-15(19-13)12-3-2-4-18-16(12)22/h2-9H,1H3,(H,18,22)(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Florida
Curated by ChEMBL
| Assay Description Inhibition of IGF1R |
J Med Chem 52: 4981-5004 (2010)
Article DOI: 10.1021/jm9002395 BindingDB Entry DOI: 10.7270/Q2P84CTD |
More data for this Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50201127
(3-(5-(1H-imidazol-1-yl)-7-methyl-1H-benzo[d]imidaz...)Show SMILES Cc1cc(cc2nc([nH]c12)-c1ccc[nH]c1=O)-n1ccnc1 Show InChI InChI=1S/C16H13N5O/c1-10-7-11(21-6-5-17-9-21)8-13-14(10)20-15(19-13)12-3-2-4-18-16(12)22/h2-9H,1H3,(H,18,22)(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IGF1 receptor |
Bioorg Med Chem Lett 17: 2317-21 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.102 BindingDB Entry DOI: 10.7270/Q2571BP2 |
More data for this Ligand-Target Pair | |