BDBM50201178 CHEMBL3963528

SMILES: OC1CCCCCCCNc2ncc3c(cn(CCCC1)c3n2)-c1ccc(cc1)S(=O)(=O)N1CCOCC1

InChI Key: InChIKey=SCCZGJNJWOJDLN-UHFFFAOYSA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50201178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50201178 (CHEMBL3963528) Show SMILES OC1CCCCCCCNc2ncc3c(cn(CCCC1)c3n2)-c1ccc(cc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C28H39N5O4S/c34-23-8-4-2-1-3-6-14-29-28-30-20-25-26(21-32(27(25)31-28)15-7-5-9-23)22-10-12-24(13-11-22)38(35,36)33-16-18-37-19-17-33/h10-13,20-21,23,34H,1-9,14-19H2,(H,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50201178 (CHEMBL3963528) Show SMILES OC1CCCCCCCNc2ncc3c(cn(CCCC1)c3n2)-c1ccc(cc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C28H39N5O4S/c34-23-8-4-2-1-3-6-14-29-28-30-20-25-26(21-32(27(25)31-28)15-7-5-9-23)22-10-12-24(13-11-22)38(35,36)33-16-18-37-19-17-33/h10-13,20-21,23,34H,1-9,14-19H2,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro3 (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50201178 (CHEMBL3963528) Show SMILES OC1CCCCCCCNc2ncc3c(cn(CCCC1)c3n2)-c1ccc(cc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C28H39N5O4S/c34-23-8-4-2-1-3-6-14-29-28-30-20-25-26(21-32(27(25)31-28)15-7-5-9-23)22-10-12-24(13-11-22)38(35,36)33-16-18-37-19-17-33/h10-13,20-21,23,34H,1-9,14-19H2,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Flt3 (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50201178 (CHEMBL3963528) Show SMILES OC1CCCCCCCNc2ncc3c(cn(CCCC1)c3n2)-c1ccc(cc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C28H39N5O4S/c34-23-8-4-2-1-3-6-14-29-28-30-20-25-26(21-32(27(25)31-28)15-7-5-9-23)22-10-12-24(13-11-22)38(35,36)33-16-18-37-19-17-33/h10-13,20-21,23,34H,1-9,14-19H2,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of MerTK (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50201178 (CHEMBL3963528) Show SMILES OC1CCCCCCCNc2ncc3c(cn(CCCC1)c3n2)-c1ccc(cc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C28H39N5O4S/c34-23-8-4-2-1-3-6-14-29-28-30-20-25-26(21-32(27(25)31-28)15-7-5-9-23)22-10-12-24(13-11-22)38(35,36)33-16-18-37-19-17-33/h10-13,20-21,23,34H,1-9,14-19H2,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of human MerTK kinase domain (1585 to 3000 residues) expressed in HEK293 cells co-expressing rat EGFR LBD assessed as inhibition of EGF-st...				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair