BDBM50201180 CHEMBL3910180

SMILES: COc1cc(ccc1-c1cccc2cc(ccc12)S(=O)(=O)Nc1cscn1)C(F)(F)F

InChI Key: InChIKey=AQLNQNFYWXYQCH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201180   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50201180 (CHEMBL3910180) Show SMILES COc1cc(ccc1-c1cccc2cc(ccc12)S(=O)(=O)Nc1cscn1)C(F)(F)F Show InChI InChI=1S/C21H15F3N2O3S2/c1-29-19-10-14(21(22,23)24)5-7-18(19)17-4-2-3-13-9-15(6-8-16(13)17)31(27,28)26-20-11-30-12-25-20/h2-12,26H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells assessed as inhibition of sodium current at holding potential of -125 mV measured for 3 to 5 min...				ACS Med Chem Lett 7: 1062-1067 (2016) Article DOI: 10.1021/acsmedchemlett.6b00243 BindingDB Entry DOI: 10.7270/Q2VM4F65
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50201180 (CHEMBL3910180) Show SMILES COc1cc(ccc1-c1cccc2cc(ccc12)S(=O)(=O)Nc1cscn1)C(F)(F)F Show InChI InChI=1S/C21H15F3N2O3S2/c1-29-19-10-14(21(22,23)24)5-7-18(19)17-4-2-3-13-9-15(6-8-16(13)17)31(27,28)26-20-11-30-12-25-20/h2-12,26H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells assessed as inhibition of sodium current at holding potential of -125 mV measured for 3 to 5 min...				ACS Med Chem Lett 7: 1062-1067 (2016) Article DOI: 10.1021/acsmedchemlett.6b00243 BindingDB Entry DOI: 10.7270/Q2VM4F65
					More data for this Ligand-Target Pair