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SMILES: Cc1nc(NC(=O)c2cccc3oc(=O)[nH]c23)cs1

InChI Key: InChIKey=ODMBDPAWRLGDOQ-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201486   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50201486
PNG
(CHEMBL391955 | N-(2-methylthiazol-4-yl)-2-oxo-2,3-...)
Show SMILES Cc1nc(NC(=O)c2cccc3oc(=O)[nH]c23)cs1
Show InChI InChI=1S/C12H9N3O3S/c1-6-13-9(5-19-6)14-11(16)7-3-2-4-8-10(7)15-12(17)18-8/h2-5H,1H3,(H,14,16)(H,15,17)
PDB
MMDB

KEGG

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PC cid
PC sid
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PubMed
 250n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Binding affinity to mGluR5

Bioorg Med Chem Lett 17: 1302-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.006
BindingDB Entry DOI: 10.7270/Q2H41R3G
More data for this
Ligand-Target Pair